AT322740B - Verfahren zur herstellung von 7-(d-alfa-amino-1,4-cyclohexadien-1-ylacetamido)-desacetoxycephalosporansäuredihydrat - Google Patents

Verfahren zur herstellung von 7-(d-alfa-amino-1,4-cyclohexadien-1-ylacetamido)-desacetoxycephalosporansäuredihydrat

Info

Publication number
AT322740B
AT322740B AT425673A AT425673A AT322740B AT 322740 B AT322740 B AT 322740B AT 425673 A AT425673 A AT 425673A AT 425673 A AT425673 A AT 425673A AT 322740 B AT322740 B AT 322740B
Authority
AT
Austria
Prior art keywords
ylacetamido
desacetoxycephalosporanic
cyclohexadien
alfa
dihydrate
Prior art date
Application number
AT425673A
Other languages
German (de)
English (en)
Original Assignee
Squibb & Sons Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Squibb & Sons Inc filed Critical Squibb & Sons Inc
Application granted granted Critical
Publication of AT322740B publication Critical patent/AT322740B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D501/00Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/207-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/227-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with radicals containing only hydrogen and carbon atoms, attached in position 3
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT425673A 1972-06-01 1973-05-15 Verfahren zur herstellung von 7-(d-alfa-amino-1,4-cyclohexadien-1-ylacetamido)-desacetoxycephalosporansäuredihydrat AT322740B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00258767A US3819620A (en) 1972-06-01 1972-06-01 7-(d-alpha-amino-1,4-cyclohexadien-1-ylacet-amido)desacetoxycephalosporanic acid dihydrate

Publications (1)

Publication Number Publication Date
AT322740B true AT322740B (de) 1975-06-10

Family

ID=22982041

Family Applications (1)

Application Number Title Priority Date Filing Date
AT425673A AT322740B (de) 1972-06-01 1973-05-15 Verfahren zur herstellung von 7-(d-alfa-amino-1,4-cyclohexadien-1-ylacetamido)-desacetoxycephalosporansäuredihydrat

Country Status (30)

Country Link
US (1) US3819620A (en])
JP (1) JPS5544754B2 (en])
KR (1) KR820001606B1 (en])
AR (1) AR196669A1 (en])
AT (1) AT322740B (en])
AU (1) AU475833B2 (en])
BE (1) BE800373A (en])
BR (1) BR7303959D0 (en])
CA (1) CA1004220A (en])
CH (1) CH582185A5 (en])
CS (1) CS178428B2 (en])
DD (1) DD106181A5 (en])
DE (1) DE2326880C2 (en])
EG (1) EG11139A (en])
ES (1) ES415420A1 (en])
FI (1) FI57952C (en])
FR (1) FR2186234B1 (en])
GB (1) GB1426266A (en])
HU (1) HU167052B (en])
IE (1) IE38750B1 (en])
IL (1) IL42243A (en])
IN (1) IN138787B (en])
IT (1) IT1068202B (en])
NL (1) NL176267C (en])
NO (1) NO144849C (en])
PL (1) PL87262B1 (en])
RO (2) RO63443A (en])
SE (1) SE409714B (en])
SU (1) SU465793A3 (en])
ZA (1) ZA732889B (en])

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5725557B2 (en]) * 1972-11-17 1982-05-29
CH619233A5 (en]) * 1975-07-31 1980-09-15 Ciba Geigy Ag
US4054738A (en) * 1975-12-22 1977-10-18 Eli Lilly And Company Sodium cefamandole crystalline forms
US4946838A (en) * 1981-07-13 1990-08-07 E. R. Squibb & Sons, Inc. Crystalline anhydrous aztreonam
NZ220764A (en) * 1986-07-02 1989-09-27 Shionogi & Co Crystalline form of 7beta((z)-2-(2-aminothiazol-4-yl)-4- carboxybut-2-enoylamino)-3-cephem-4-carboxylic acid and pharmaceutical compositions
US4977257A (en) * 1988-11-14 1990-12-11 Eli Lilly And Company DMF solvates of a β-lactam antibiotic
US5278157A (en) * 1989-07-10 1994-01-11 Gema, S.A. Stable cephradine hydrate
ES2063974T3 (es) * 1989-07-10 1995-01-16 Chemferm Vof Una nueva forma estable de cefradina, un proceso para su produccion y compuestos intermedios usados en tal proceso.
IT1289955B1 (it) * 1997-02-21 1998-10-19 Solchem Italiana Spa Acyclovir sale sodico biidrato e sua preparazione
CN1326860C (zh) * 2002-08-06 2007-07-18 北京化工大学 头孢拉定晶体以及制备头孢拉定的方法
BRPI0412302A (pt) * 2003-07-03 2006-06-13 Dsm Ip Assets Bv processo para a preparação de cefradina
CN104688713A (zh) * 2015-03-20 2015-06-10 江苏亚邦强生药业有限公司 一种头孢拉定胶囊剂及其制备方法
CN112206217A (zh) * 2020-10-21 2021-01-12 迪沙药业集团有限公司 一种头孢拉定药物组合物及其制备方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3485819A (en) * 1968-07-02 1969-12-23 Squibb & Sons Inc Alpha-amino-cyclohexadienylalkylene-penicillins and cephalosporins

Also Published As

Publication number Publication date
AR196669A1 (es) 1974-02-12
IE38750L (en) 1973-12-01
ES415420A1 (es) 1976-02-16
NL176267C (nl) 1985-03-18
FR2186234A1 (en]) 1974-01-11
SU465793A3 (ru) 1975-03-30
FI57952C (fi) 1981-09-07
IE38750B1 (en) 1978-05-24
IT1068202B (it) 1985-03-21
RO68286A (ro) 1980-12-30
JPS4941520A (en]) 1974-04-18
RO63443A (fr) 1978-07-15
CH582185A5 (en]) 1976-11-30
AU475833B2 (en) 1976-09-02
NL7307321A (en]) 1973-12-04
PL87262B1 (en]) 1976-06-30
US3819620A (en) 1974-06-25
DD106181A5 (en]) 1974-06-05
DE2326880C2 (de) 1982-04-15
FR2186234B1 (en]) 1976-10-22
BE800373A (fr) 1973-12-03
AU5507473A (en) 1974-11-07
IL42243A0 (en) 1973-07-30
CA1004220A (en) 1977-01-25
NO144849B (no) 1981-08-17
BR7303959D0 (pt) 1974-08-29
SE409714B (sv) 1979-09-03
JPS5544754B2 (en]) 1980-11-13
GB1426266A (en) 1976-02-25
HU167052B (en]) 1975-07-28
DE2326880A1 (de) 1973-12-20
NO144849C (no) 1981-11-25
KR820001606B1 (ko) 1982-09-08
IL42243A (en) 1975-10-15
FI57952B (fi) 1980-07-31
ZA732889B (en) 1974-04-24
EG11139A (en) 1978-03-29
CS178428B2 (en]) 1977-09-15
IN138787B (en]) 1976-03-27

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Legal Events

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ELA Expired due to lapse of time